Custom-Compounded Acne Treatments


Clearer skin starts with personalized dermatology care

Acne doesn’t care if you’re 14 or 44.

It pops up during high-stress weeks, during hormonal chaos, after long flights, and sometimes for no clear reason at all—and it can derail your mood, your plans, and your self-confidence.

And while standard treatments work for some, many people cycle through creams, gels, and antibiotics that irritate the skin or simply don’t address their biology.

At Alpine Compounding Pharmacy, we help you break that cycle with custom-formulated acne medications, tailored to your skin type, sensitivity, acne severity, and provider’s treatment plan.

Whether you struggle with persistent breakouts, cystic acne, mask-induced irritation, or stubborn hormonal flare-ups, we create precise formulations that your skin can actually tolerate and respond to.

Explore all Dermatology Compounding →

Why Compounded Acne Treatments Make a Difference

No two people experience acne the same way. Your triggers, whether hormonal, bacterial, stress-related, or sensitivity-based, are unique. But most commercial acne medications come in fixed strengths, preservatives, or combinations that may be too harsh, too weak, or simply unavailable.

Custom compounding changes that.

Benefits of Choosing Personalized Acne Formulations

✔ Tailored strengths for sensitive, resistant, or combination skin
✔ Multi-ingredient blends that simplify routines and improve adherence
✔ Options for patients who cannot tolerate commercial products
✔ Preservative-free or hypoallergenic bases
✔ Access to medications in the exact percentages your dermatologist recommends
✔ Child, teen, and adult-friendly formulas

Every dermatology medication we compound is made in a USP-compliant facility with pharmaceutical-grade ingredients for safety and consistency.

The Acne Medications We Compound

We prepare topical and oral custom acne treatments that address inflammation, bacteria, clogged pores, hormones, and scarring.

  1. Topical Antibiotics (Custom Strengths)
  • Clindamycin
  • Erythromycin
  • Metronidazole (for acne + rosacea overlap)
  1. Benzoyl Peroxide (BPO) – Customised Percentages

Commercial BPO is only available in fixed strengths.  We compound a wide range and lower-irritation blends for sensitive skin.

Fixed-dose combinations of adapalene 0.1%/benzoylperoxide 2.5% may also help. 

  1. Retinoids

Custom strengths to reduce irritation while improving results:

  • Tretinoin 0.0125%, 0.025%, 0.05%, 0.1%
  • Adapalene custom %
  • Tazarotene low-strength options
  1. Compounded Oral Acne Medications
  • Low-dose doxycycline
  • Spironolactone capsules (for hormonal acne)
  • Zinc + anti-inflammatory blends
  1. Scar, Pigmentation & Post-Acne Support
  • Kojic acid blends
  • Tretinoin for collagen remodelling
  • Skin-brightening formulation blends

For help with other conditions linked to cycles, PCOS, postpartum changes, or hormonal imbalance, you may find helpful support on our Women’s Health page. 

When Acne Isn’t Just Skin-Deep: How LDN Helps Calm the Invisible Triggers

For many people, acne isn’t just clogged pores or excess oil. It’s the mood swings, the stress, the sleepless nights, the flare-ups that show up exactly when you least expect them.

This is where Low-Dose Naltrexone (LDN) can help. 

Even though LDN isn’t a traditional acne medication, It works internally, supporting the systems that influence how your skin behaves on the surface.

✔ Calms chronic inflammation

✔ Improves stress resilience

✔ Supports hormonal balance indirectly

✔ Better sleep = better skin

Side Effects of Compounded LDN 

Most people tolerate Low-Dose Naltrexone (LDN) well; mild side effects like vivid dreams or temporary sleep changes may occur as your dose adjusts.

When to Take Compounded LDN

LDN is typically taken once daily in the evening, allowing your body to regulate inflammation, endorphins, and stress pathways overnight.

Curious about how compounded LDN regulates inflammation and stress pathways? Explore the LDN main page for a full breakdown.

Who Benefits From Custom Acne Medications?

Custom-compounded acne formulas are ideal for:

  • Sensitive or reactive skin
  • Cystic, hormonal, or adult acne
  • Acne with pigmentation or scarring
  • Acne + rosacea, eczema, or autoimmune overlap
  • Teens & pre-teens

If you’d like to explore other personalised skin treatments, our Dermatology Compounding page offers options for pigmentation, rosacea, eczema, and more.

Why Choose Alpine Compounding Pharmacy?

At Alpine, we combine dermatology expertise with precise, pharmacy-grade compounding so every formula matches your skin’s biology and your provider’s treatment plan.

Precision Compounding for Dermatology

Custom strengths, multi-ingredient blends, and gentle bases for sensitive or complex skin.

✔ Made-to-Order Formulations

Your prescription is crafted fresh—never mass-produced, never pre-filled.

✔ Barrier-Friendly, Preservative-Aware Options

We prioritise tolerability, especially for acne patients prone to irritation or dryness.

✔ Collaborative Care With Dermatologists

Providers trust us to prepare exact formulations that commercial brands simply don’t offer.

✔ Discreet, Patient-Centered Support

From teens to adults managing stress, hormones, or autoimmune triggers, we offer judgment-free guidance every step of the way.

Available at Alpine Compounding Pharmacy, a certified compounding pharmacy in Colorado. We ship across the U.S.

FAQs: Custom Acne Treatments

Q: Do I need a prescription for compounded acne medications?
Yes. Your dermatologist or healthcare provider will specify the exact ingredients and strengths. We prepare your medication according to their plan.
Q: Are compounded acne creams gentler than commercial ones?
They can be. Because we adjust the base, strength, and pH, custom formulations are often far better tolerated—especially for sensitive or reactive skin.
Q: Can you combine multiple acne medications into one product?
Yes. Many patients do better with a single formula that includes a retinoid, antibiotic, niacinamide, azelaic acid, or benzoyl peroxide—customised to your skin.
Q: Is this suitable for teens?
Absolutely. Teens often need lower strengths and hypoallergenic bases. We tailor each formula to age, skin type, and sensitivity.
Q: Are oral medications like spironolactone or doxycycline compounded too?
Yes. We prepare customised capsules for patients who need specific doses, dye-free formulations, or easier-to-take versions.
Q: How long does it take to see results?
Most patients notice improvements in 6–12 weeks. Customised formulas often improve consistency and tolerability—two key factors in achieving clear skin.
Q: Can compounded medications help with acne scars or pigmentation?
Yes. Ingredients like tretinoin, azelaic acid, hydroquinone, kojic acid, and niacinamide can be combined to target marks and discoloration while preventing new breakouts.

Based in Arvada, CO | Serving Colorado & nationwide
Explore our Dermatology Compounding Services →

 


Ready for Clearer, Calmer Skin?

Custom acne compounding gives you targeted treatment that matches your skin—not a generic formula.