Low Dose Naltrexone
Relieve Pain, Restore Life with Low Dose Naltrexone. Expertly Compounded LDN for Optimal Pain Management.Â

IntroductionÂ
Are you struggling with chronic pain, autoimmune disorders, or the side effects of cancer treatment?Â
Chronic pain is a condition that affects more than 50 million people in the U.S., making it challenging to treat effectively. With concerns about the risks of using opioids, there is a growing interest in finding safer, non-opioid treatments for chronic pain that have fewer side effects.Â
If you've been searching for an effective and personalized approach, you might find relief with Low Dose Naltrexone (LDN). Originally approved by the FDA for treating opioid and alcohol addiction, LDN is now being studied for its potential to help with chronic pain.
How Low-Dose Naltrexone Works
When damaged, nerves can trigger cells in the brain and spinal cord called glial cells. These cells release chemicals that cause inflammation and make the body more sensitive to pain, leading to chronic pain. Low-dose naltrexone for pain is a popular treatment choice because it reduces chronic pain by calming inflammation in the nervous system.
Although Naltrexone is mainly known for blocking opioid receptors in the brain, at low doses, it does much more. LDN also blocks specific receptors in the nervous system that play a role in inflammation, which helps reduce pain. It can also slow cell growth, which might be useful in treating certain cancers.
Some of the key benefits of low-dose naltrexone include its ability to reduce inflammation, balance the immune system, and provide pain relief without the risk of addiction.
The most common low-dose naltrexone dosage, depending on the treated condition, ranges from 1.5 mg to 4.5 mg daily.
Conditions LDN Can Help Treat?
LDN has shown promise in treating various types of chronic pain and inflammation-related conditions, including:
- Fibromyalgia
- Chronic Back Pain
- Migraines and Chronic Headaches
- Arthritis-related Pain
- Irritable Bowel Syndrome (IBS)
- Inflammatory Bowel Disease (IBD)
- Crohn's Disease
- Ulcerative Colitis
- Multiple sclerosis (MS)
- Complex regional pain
- Neuropathic pain (like diabetic nerve pain)
- Cancer-related pain syndrome (CRPS)
- Alcohol Use Disorder
- Substance Use Disorders
- Endometriosis
- Polycystic Ovary Syndrome (PCOS)
- Chronic Pelvic Pain
- Psoriasis
- Eczema (Atopic Dermatitis)
- Lichen Planus
- Hashimoto’s ThyroiditisÂ
By helping to manage inflammation and reduce pain, LDN offers a promising alternative for those seeking relief from chronic pain without relying on opioids.
Some other uses of low-dose naltrexone:
- Low-dose naltrexone and cancer research suggest that it may help slow down the growth of certain types of cancer by affecting cell proliferation.
- Low-dose naltrexone for autoimmune conditions works by calming down an overactive immune response, making it useful for diseases like lupus.
- Low-dose naltrexone autism studies are looking into its potential benefits for improving behaviour and reducing inflammation in autistic individuals.
- Low-dose naltrexone for long COVID is being explored to manage lingering symptoms by reducing inflammation in the body.
- Low-dose naltrexone anxiety relief has been reported due to its ability to calm the immune system and lower stress hormone levels.
Our personalized LDN compounding services ensure precise and accurate dosing, allowing you to receive therapeutic benefits tailored to your specific needs. We offer multiple formulation options to make treatment convenient and effective.

Safety and Efficacy of Low-Dose Naltrexone
The safety profile of Low Dose Naltrexone is well-documented, with most patients experiencing minimal side effects when the dosage is tailored to their needs. Some individuals may initially experience mild symptoms like headaches or sleep disturbances, but these typically subside as the body adjusts to the therapy.
Our team at Alpine Compounding Pharmacy takes a personalized approach to monitoring your response to LDN, ensuring that any adverse effects are quickly addressed. Regular follow-ups help us fine-tune your treatment to maintain the ideal balance.
Benefits of Customized LDN Therapy
When it comes to Low Dose Naltrexone, one size does not fit all. Here’s why customized LDN therapy from Alpine Compounding Pharmacy can make a significant difference:
- Precise Dosing Adjustments: Our compounding services allow us to adjust the dosage strength to meet your specific health requirements, minimizing potential side effects and optimizing therapeutic benefits.
- Enhanced Absorption and Convenience: We compound LDN into various forms such as capsules, tablets, and sublingual troches, designed to maximize absorption and ensure ease of use.
- Reduced Side Effects: Customizing the dosage of LDN helps lower the risk of side effects like gastrointestinal discomfort or mood changes, which are more common with one-size-fits-all treatments.
Get the Facts: Low Dose Naltrexone Explained
Q: What should I avoid when taking low-dose naltrexone?Â
A: Low-dose naltrexone and alcohol should generally not be combined, as alcohol can interfere with the medication's effectiveness.
Q: What are the side effects of low-dose naltrexone?Â
A: Common side effects include mild headaches, vivid dreams, sleep disturbances, and digestive discomfort. There are very few low-dose naltrexone dangers, and it is considered a safe, non-addictive alternative to opioids.
Q: How long do low-dose naltrexone side effects last?Â
A: Side effects are typically short-lived, lasting from a few days to a couple of weeks as your body adjusts. Current research suggests that LDN has minimal long-term side effects, making it a safe option for extended use.

Q: What is the typical dosage of low-dose naltrexone?Â
A: The usual dosage of LDN is between 1.5 mg and 4.5 mg per day, depending on the condition being treated.
Q: Is it difficult to come off of low-dose naltrexone? Â
A: Stopping low-dose naltrexone should always be done under a healthcare provider’s guidance to avoid any potential withdrawal effects.
Q: Why is low-dose naltrexone taken at night?
A: LDN at night may improve your body's natural endorphin production and regulate sleep.
Most people take their naltrexone tablet in the morning, although there's no specific time requirement.Â
Taking it after breakfast can be a helpful routine, reinforcing their commitment to treating opioid or alcohol use disorder. Eating with the tablet might also reduce side effects like nausea or stomach pain.
Be aware that naltrexone can also cause drowsiness, fatigue, or dizziness, affecting your ability to drive or use machinery.
Q: Can low-dose naltrexone be taken with alcohol?
A: If you drink alcohol while taking naltrexone, the medication blocks the "buzz" or euphoric effects of alcohol. This helps people with alcohol use disorder reduce their drinking, manage cravings, and stay in treatment.Â
However, naltrexone does not prevent impairment, so you should not drink alcohol and attempt activities like driving. Naltrexone is not an opioid; it works by blocking opioid receptors in the body, helping treat both alcohol and opioid use disorders without causing a high or withdrawal when you stop taking it.
Q: Does low-dose naltrexone block cannabinoid receptors?
A: Low-dose naltrexone (LDN) does not block cannabinoid receptors, which are the parts of your brain that respond to cannabis or marijuana. Instead, LDN mainly works on other receptors in the body called opioid receptors and Toll-like receptors. By targeting these, LDN helps reduce inflammation and calm down the nervous system, which can help with pain and immune-related conditions. This means if you're using cannabis, LDN won't directly interfere with how your body reacts to it, but it will still focus on reducing your pain and inflammation through other pathways.
Q: Is low-dose naltrexone covered by insurance?
A: Insurance coverage for LDN varies, so it’s best to check with your provider to see if it’s included in your plan.
Q: Where can I buy low-dose naltrexone (LDN)?
A: LDN can be obtained through a prescription from a healthcare provider and is often made by compounding pharmacies.
Q: What are the starting doses of low-dose naltrexone?
A: The starting dose for most people is usually between 1.5 mg and 3 mg, gradually increasing based on the individual's response.
Q: Is low-dose naltrexone (LDN) available over the counter?
A: No, LDN is unavailable over the counter and requires a prescription from a healthcare provider.
Q: What are the drug interactions with low-dose naltrexone?
A: LDN may interact with opioid medications, so it’s essential to discuss all medications with your healthcare provider before starting LDN.
Q: How does low-dose naltrexone help with chronic fatigue syndrome?
A: LDN may help reduce fatigue and improve energy levels by reducing inflammation and regulating the immune system.
Q: Can low-dose naltrexone help with depression?
A: Yes, LDN may help reduce symptoms of depression by boosting endorphin levels and lowering inflammation in the brain.
Q: Can low-dose naltrexone (LDN) help with weight loss?
A: Some users have noted low-dose naltrexone and weight loss due to its ability to regulate hormones and reduce inflammation, which may lead to weight loss.
Our Compounding Process for Low Dose NaltrexoneÂ
At Alpine Compounding Pharmacy, we start with a thorough consultation to understand your health needs and goals. From there, we collaborate with your healthcare provider to design a personalized LDN plan. Our pharmacists meticulously prepare each dose in our state-of-the-art lab, ensuring the highest standards of quality and effectiveness.
Take Control of Your Chronic Pain and Autoimmune Health
Don’t let chronic pain or autoimmune conditions hold you back. Discover how Low Dose Naltrexone from Alpine Compounding Pharmacy can transform your health journey.
Contact us today to learn more about personalized LDN therapy and how we can help you achieve the best version of yourself.