Erectile Dysfunction: What It Is & Why It Happens

Understand the Root Cause, So You Can Take the Right Steps Forward.
Erectile dysfunction (ED) can feel like it sneaks up on you. Maybe it started once or twice. Maybe it’s becoming more common. Either way, it’s not something to ignore—and it’s definitely not something you have to “just live with.”
At Alpine Compounding Pharmacy, we help men go beyond short-term fixes. We start by helping you understand what’s happening, why it’s happening, and how to choose the right treatment—whether that’s Trimix injections, hormone therapy, or lifestyle change.
What Exactly Is Erectile Dysfunction?
ED is the persistent difficulty in getting or keeping an erection firm enough for sexual intercourse.
It’s more than a bedroom problem. It can affect your confidence, relationships, and mental health—and sometimes, it’s the first visible sign of an underlying medical condition.
According to experts, occasional ED isn’t uncommon. Still, when it happens frequently, it could be a sign of poor blood flow, nerve damage, hormonal imbalance, or even early heart disease.
How Common Is It?
- Affects 1 in 5 men over 40, and more than half of men over 50 will experience some degree of ED.
- Among men with diabetes, 30% to 90% may experience ED, depending on duration and control of blood sugar.
- In nearly 1 in 3 diabetic men, ED is the first noticeable symptom of the disease.
The global prevalence is expected to reach over 300 million men.

What Causes Erectile Dysfunction?
ED is rarely caused by “just one thing.” It’s usually a combination of physical, hormonal, emotional, and even lifestyle-related triggers.
Here’s a breakdown:
Circulatory Issues
- Cardiovascular disease
- High blood pressure
- Atherosclerosis (narrowed arteries)
These affect the ability of blood to flow properly to the penis.
Nerve-Related Damage
- Diabetes-related neuropathy
- Pelvic surgery (especially prostatectomy)
- Spinal cord injury
When nerve signals don’t travel well, arousal and response are disrupted.
Hormonal Imbalance
- Low testosterone (Low T)
- Thyroid dysfunction
Low testosterone can reduce libido and affect erectile strength. We offer Testosterone Replacement Therapy when appropriate.
Psychological Factors
- Performance anxiety
- Depression
- Relationship strain
Even in healthy men, anxiety can lead to a self-perpetuating cycle of ED.
Medications & Substances
- Antidepressants
- Blood pressure medications
Alcohol, smoking, and recreational drugs
ED Might Be a Sign of Something Bigger
What Your Erection Can Tell You About Your Heart
It might sound surprising, but trouble in the bedroom can sometimes be the first clue that something deeper is going on—like a heart issue.
Erectile dysfunction (ED) doesn’t always mean heart disease. But when it appears without an obvious cause, like injury or medication, it may be an early warning sign of blood vessel problems, even before other symptoms show up.
Research shows that ED and heart disease share the same risk factors—and often, the same root cause: poor blood flow.
How Are ED and Heart Problems Connected?
Doctors used to believe that ED was mainly caused by plaque buildup (atherosclerosis) narrowing the arteries that supply the penis. That’s still part of the story.
But now, experts also point to a problem in the endothelium—the inner lining of blood vessels. When this lining doesn’t function properly:
- Blood flow becomes impaired
- The ability to dilate arteries is reduced
- Erections become harder to achieve and sustain
This same issue affects the arteries of the heart, increasing the risk of angina, heart attack, or other cardiovascular issues.
What Your Erection Can Tell You About Your Heart
If you’re experiencing ED, don’t just treat the symptom—screen for the cause.
Before starting any ED treatment (including medications or injections), your doctor may recommend a cardiac evaluation, especially if:
- You don’t have an obvious cause for ED (like surgery, injury, or meds)
- You’re under 50
- You’ve never had a heart work-up before
Improving heart health can also improve sexual function. In fact, lifestyle changes that help your heart often help your erections too.
Important Safety Note
If you’re already diagnosed with heart disease and take nitrates (like nitroglycerin), certain ED treatments—especially oral medications—can be dangerous.
That’s why we offer Trimix injections, a non-systemic ED treatment that works locally and is often better suited for men who can’t take pills.
→ Learn more about Trimix Injections
→ Want to assess your risks? Try our ED Symptom Checker
Want to know if you're experiencing early symptoms? Try our ED Symptom Checker
Early Clues to Watch Out For
- Erections that are less frequent or weaker
- Difficulty maintaining an erection
- Reduced libido
- Morning erections are decreasing over time
- Delayed or absent ejaculation

How We Treat ED at Alpine Compounding Pharmacy
Every man is different. Your treatment should be too. We work with your doctor to tailor a plan that fits your needs. Our solutions may include:
Oral Medications
Viagra, Cialis, Levitra—often the first step, but may not work for everyone, especially after prostate surgery or in men with diabetes.
Trimix Injections
A powerful option for those who don’t respond to pills. Learn more in our Trimix Injections: Step-by-Step Guide
Trimix is a compounded injectable medication containing:
- Alprostadil – Relaxes blood vessels and muscle tissue
- Papaverine – Enhances blood flow
- Phentolamine – Prevents blood from leaving the erection too quickly
For men who haven’t responded to oral meds, Trimix is often more reliable, fast-acting, and produces a natural-feeling erection.
Bioidentical Hormone Therapy
Customised testosterone replacement therapy for men with Low testosterone.
Lifestyle Coaching
Support with nutrition, exercise, weight loss, and smoking cessation.
Psychological Support
Referrals and suggestions for mental health therapy when needed.
How We Personalize Your ED Treatment
There’s no one-size-fits-all solution for ED. Your treatment plan depends on:
- Severity of ED (occasional vs chronic)
- Underlying causes (diabetes, prostate surgery, heart disease)
- Hormone levels (e.g., low testosterone)
- Comfort with self-injection
- Other medications or contraindications
You deserve care that fits your body, not a copy-paste prescription.
Worried it’ll be complicated or awkward? Here’s what the process actually looks like:
- Call or visit our pharmacy
- Talk to a pharmacist in a private setting
- Get referred to a physician if needed for diagnosis/labs
- We compound your treatment (e.g., Trimix, testosterone)
Learn how to use it safely at home with expert guidance.
When to Seek Help Immediately
If your ED is sudden, severe, or accompanied by:
- Chest pain
- Pelvic trauma
- Vision changes
A prolonged erection (>4 hours)
→ Seek immediate medical attention.
Why Choose Alpine Compounding Pharmacy?
We’re not a big-box pharmacy. We’re your local, discreet partner in men’s health.
✔ Custom-compounded medications with precision dosing
✔ Consultations that explain, not overwhelm
✔ Guidance on how to administer Trimix safely at home
✔ Compassionate, judgment-free care every step of the way
Explore our full treatment offering: ED & Trimix at Alpine
Frequently Asked Questions (FAQ)
Patient Perspective
“I was hesitant to even bring it up—but Alpine made it easy. No judgment, just a clear plan.”
Let’s Talk - Privately
You deserve answers. If you’re ready to start treatment—or even just ask questions—we’re here to help.